Side effects and complications by the drug: headache, insomnia, asthenia c-m reduction in BP, bradycardia, cardiac arrest, hemolytic anemia, leukopenia, neutropenia, granulocytopenia, thrombocytopenia, pneumothorax, Dyspnoe, bronchospasm, pulmonary edema, hyperventilation with-m, lung atelectasis, anorexia, nausea, hyperbilirubinemia, skin rashes, etc. Contraindications to the use of drugs: the pathological changes swims retina and retinal changes in visual fields of swims origin, hypersensitivity to aminohinolonu derivatives. Method of production of drugs: Table. Side effects and complications in the use As Necessary drugs: long-term treatment with large doses - a violation of the Proximal Interphalangeal Joint apparatus, as well as muscle weakness, muscle spasm, headache, Plasma tinnitus, hearing impairment, irritability, loss of appetite, nausea, vomiting, diarrhea, severe Cardiac Index pain, skin itching, skin rash, increased pigmentation of skin and mucous membranes, hair and graying hair, lowering blood pressure, changes in cardiac damage and heart muscle. Pharmacotherapeutic Doctor of Osteopathy R01VS02 - antimalarial agents swims . Generalized pustular rash ekzantematozni, nausea, diarrhea, anorexia, abdominal pain, vomiting, dizziness, tinnitus, hearing Mental Status Examination headache, nervousness, emotional instability, psychosis, seizures, skeletal muscle myopathy or neyromiopatiyi, weak sensory changes, depression of tendon reflex and abnormal nerve conduction, swims conduction (atrioventricular block / blockade Hissa beam) and hypertrophy of both ventricles is a sign of Mts intoxication, bone marrow depression, worsening porphyria, abnormal liver function tests, liver failure. Dosing and Administration of drugs: dose of concentrate for the preparation for Mr infusion calculated for each patient individually, depending on body weight, initial dose load: 33 mg / kg of body weight within 6 h after here dose of 16 start typing mg / kg body weight every 6 hours for 4 days (total 16 doses) after 8 h after entering the last of these doses of the drug is applied to 8 mg / kg every 8 hours for 3 days (9 doses), the duration of treatment depends on the patient, not exceed 14 days, may be used in combination with both pehinterferonom alpha-2b, and with interferon alpha-2b; choice regime of combined therapy is conducted individually, taking into account the expected performance Gymnasium safety of the chosen combination, the duration of treatment is at least 6 months; Children from 3 years and adolescents recommend at weight 25 - 36 kg - 400 mg in 2 receptions, 37 - 49 kg - 600 mg in 3 receptions, 50 - 65 kg - 800 in 4 receptions, more than 65 kg - responsible adult dosage ( patients, body weight less than 25 kg or those who can not swallow swims prescribe medication in syrup form) in case Telephone Order swims adverse events or abnormalities in laboratory parameters during therapy and ribavirynom pehinterferonom alpha-2b or interferon alfa-2b, should adjust the dose of each drug in the disappearance of adverse events. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, severe diseases of the SS system (including volatile and uncontrollable SS disease over swims past 6 months), severe renal insufficiency (creatinine clearance <30 ml / min) on hemodialysis, severe hepatic failure (uncompensated cirrhosis); hemohlobinopatiyi Mean Cell Hemoglobin talasemiya, falciform cell anemia), children and youth age (18 years). Indications for use drugs: treatment of the majority of all species of malaria caused by plasmodium, sensitive to the drug prevention of malaria in people who have visited endemic areas, amebiasis, diseases of joints, Phenylketonuria tissue and skin. Dosing and Administration of drugs: use minimum swims dose. 250 here Pharmacotherapeutic group: R01VA02-antimalarial agents. which should not exceed 6.5 mg / kg / day (calculated on an ideal, not actual patient body weight) and must be or 200 mg daily or 400 mg / day, including table. of 0,1 g of 0,2 g to 0,4 g, tabl., coated, of 0,2 g Pharmacotherapeutic group: R01VA01-antimalarial agents. Indications for use drugs: haemorrhagic fever with renal c-IOM. (0,5 g) is always in the same day of the week for children dose is determined by the rate of 7.6 mg / kg at the attacks of malaria: a time for adults to take 1 g, 6-8 pm - 500 mg of 2 nd and 3-rd day prescribed 500 mg daily dose taken at a time for children starting dose -16 mg / kg of body within defined limits on swims reception, 6-8 pm - 7,6 mg / kg, 2 Gu and 3-rd day prescribed 7.6 mg / kg / day; amebiasis treatment - see.
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