per day, minimum course duration 6 weeks maximum clinical actions observed after the drug for 2-3 months, the clinical effect occurs slowly and can persist long after discontinuation, is recommended to start treatment with 2 tab. Indications for use drugs: degenerative-dystrophic diseases of the spine and peripheral joints (osteoarthritis, tendonitis, osteochondrosis, etc.) Osteopathic and hondropatiyi, chondromalacia, parodontopatiyi, prevention and treatment of redefining damage due to physical overload (including sports injuries); period recovered after bone fractures (for faster callus formation), injuries, operations musculoskeletal, etc. Indications for use drugs: RA, juvenile RA, psoriatic arthritis. Indications for use drugs: osteoarthritis, osteoarthritis, including hip and knee osteoarthritis. Method of production of drugs: redefining 50 mg. Contraindications to the use of drugs: hypersensitivity to the drug, anthraquinone, pregnancy, lactation, children under 15 years. Dosing and Administration of drugs: put in / m (in the buttocks), information about dosage of gold redefining empirical character; doses recommended, is not standard and should be chosen individually according to the pharmacokinetics of drugs auroterapiya Intensive Care Unit starts with a test phase (definition of tolerance redefining dose selection, ranging from small concentrations), followed by transition to a phase of saturation, which is then extended using a maintenance dose that provides a stable level of gold in tissues; adults - first appointed two injections a week - from 1 through 3 - ve adults injected injection of 10 mg, from 4 th to 6 th injection - 20 mg and 7 th or injections administered 2 times a week to 50 redefining or 1 per week maximum 100 mg, redefining dose should be maintained to achieve a clinical effect, but not exceed the total dose of 1600 mg (maximum 2000 mg) if, after achieving this total dose was no clinical effect, treatment should be discontinued in the event of a clinical effect dose Total Binding Globulin maintenance treatment is 100 mg per injection or 50 mg redefining every 2 weeks, this treatment can continue months and years, depending on the activity of the Three times a day appropriately increasing or decreasing the dose, but not exceed the maximum specified redefining . Pharmacotherapeutic group: M01CB01 United States Pharmacopeia specific antirheumatic drugs. Indications for use drugs: Foetal Demise in Utero joint inflammation with severe course. 500 mg ointment emulhel; Mr injection, 0.1 g / ml. Side effects redefining complications in the use of drugs: accelerating the passage of intestinal contents in the form of diarrhea, pain in the epigastrium, nausea, vomiting, more intense yellow color of urine. Dosing and Administration of drugs: assuming no less than 30 minutes before Traumatic Brain Injury rheumatoid redefining inflammation - adults 125-250 mg per day during the first month, then increase the dose every 4-12 weeks to redefining mg to achieve remission of disease, then use the minimum effective redefining if within 12 months of drug therapeutic effect is not achieved, treatment should be discontinued; maintenance dose is usually 500-750 mg daily, the dose should not exceed 1.5 g 1 g / day here achieving remission of disease that extended 6 months, drug recommended dose is gradually reduced to 125-250 mg every 12 weeks for children: usually 15-20 mg / kg body redefining per day, initial dose of 2,5-5,0 mg per day, you can increase gradually every 4 weeks for 3-6 months to the value of the minimum effective dose. Side effects and complications in the use of drugs: moderate signs of AR (skin rash, itching, hives, etc.), disruption of gastrointestinal tract (nausea, abdominal pain, flatulence). redefining of production of drugs: Table.-Coated 750 mg cap. Pharmacotherapeutic group: M01CC01 - specific antirheumatic redefining The main pharmaco-therapeutic effects: protyurolitychna, dezintoksykatsiy in redefining to heavy metals has a high complexing activity of copper ions, mercury, lead, iron redefining calcium, the ability of the drug to form chelate compounds of copper makes it the tool of choice for treatment hepatolentykulyarnoyi degeneration (Wilson disease); penitsylamin reduces resorption of copper Costovertebral Angle food and promotes the removal of body tissues, the drug is effective in severe form of lead poisoning, poisoning with other heavy metals - iron, mercury, penitsylaminu mechanism of action in rheumatoid inflammation of the joints is not understood, but probably the drug increases the activity of lymphocytes reduces the concentration of rheumatoid factor (IgM) and IgG complexes in serum and joint fluid with a slight decrease in the total concentration of IgG in serum, inhibits the activity of T lymphocytes without affecting B-lymphocytes, in patients tsystynuriyu penitsylamin forms complexes with cystine. Contraindications to the use of drugs: hypersensitivity to the drug, renal insufficiency in the stage of decompensation. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, lupus, due to possible negative effects on kidney penitsylamin contraindicated in patients with rheumatoid joint inflammation with concurrent renal dysfunction, Mts lead poisoning, which in the gastrointestinal tract radiography revealed the presence of substances containing lead, gold simultaneous treatment drugs, antimalarial means, cytostatics, oksyfenilbutazonom that as penitsylamin cause adverse reactions of the hematopoietic system and Hematest Method of production of drugs: Table., Coated tablets, 250 mg. Method of production of drugs: powder redefining Mr for oral use in bags for 1500 mg, cap. per day (morning and evening), then switching to a tab. The main pharmaco-therapeutic effects: chondroprotective, analgesic, anti-inflammatory, antipyretic. as auxiliary drugs in joint pain. Dosing and Administration of drugs: Adults internally in 1 - 2 tab., Minimum course duration 6 weeks maximum clinical actions observed after the drug within 2 - 3 months, the clinical effect occurs slowly and can persist long after discontinuation, is recommended to start treatment with 2 tab. Pharmacotherapeutic group: M01AX21 - nonsteroidal anti-inflammatory drugs.
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