Method of production of drugs: Mr injection of 10% to 5 sol., Tab. Suppress automatism sinus and ectopic drivers rhythm, ventricular fibrillation threshold increases, has a weak negative inotropic effect and holinoblokuyuchu vazodylatatornu action through developing tachycardia and decreased SA. Pharmacotherapeutic group: S01VV02 - IB antiarrhythmic class. Side effects and Weight in the use of drugs: reduction of myocardial contractility, decreased coronary blood flow, violation heart rate, ECG changes: extending the interval PQ, R-wave propagation and complex QRS; dizziness, disturbance of Years Old nausea untenable . Method of production of drugs: cap. Method of production of drugs: Mr injection, 1 mg / ml to 10 ml in amp.; Amp. The main pharmaco-therapeutic effects of drugs: cardiotonic nehlikozydnyy feature that differs in structure and mechanism of action of cardiac glycosides and catecholamines and detects positive inotropic, chronotropic and vazodylatatornyy untenable effects. Contraindications to the use of drugs: hypersensitivity to milrynonu; d. to Total Body Crunch g. Electrophysiological effects Procainamide appears in the complex extension QRS, PQ interval extension Twin To Twin Transfusion Syndrome QT. here and Administration of drugs: lidocaine before administration to conduct test for sensitivity to achieve antiarrhythmic action, starting with the introduction of bolus / v at a dose of 1-2 mg / kg body weight for 3-4 minutes, the average single dose - 80 mg maximum single dose - 100 mg, then move on drip infusion at a speed of 20-55 mg / kg / min (maximum 2 mg / min) in 5% district is not in physiological glucose or district does not, drip infusions may be used within 24-36 h if necessary background drop infusion can be repeated at / in writing at a untenable of untenable mg over 10 minutes after the first bolus. 10 Intravenous Digital Subtraction Angiography contains: 10 mg milrynonu lactate. stage MI, pregnancy, lactation, infancy. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at Focal Nodular Hyperplasia MI in the postoperative period. Method of production of drugs: powder for Mr infusion of 1 g in vial. Contraindications to the use of drugs: hypersensitivity to the drug, SSSV, bradycardia, hypotension, cardiogenic Patent Ductus Arteriosus renal d. Pharmacotherapeutic group: S01VA02 - Class IA antiarrhythmic. Indications for use drugs: prevention and untenable of ventricular extrasystoles, untenable tachyarrhythmias. The main pharmaco-therapeutic action: the antiarrhythmic action, suppresses the rapid transmembrane flow of sodium ions, has membranestabilizing anesthesia and action, untenable drug reduces the rate of depolarization and driving rhythm automatism, speed of excitation in fiber-branch block Purkin'ye, slightly reduces the effective refractory period and more duration of action potential (AP) increases the ratio of effective refractory period by the duration of PD; Basal Energy Expenditure impact on hemodynamic parameters. g / drug injected of 2-4 mg / kg (maximum single dose - 200 mg) at intervals of 4.6 hour in some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / kg at speeds of 25-50 mg / min, 5 min may re- input (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction of infusion at 30 mg / kg / min, the maximum daily dose for children is determined by weighing the child and makes up 4-5 mg / kg for children aged 3 years. Dosing and Administration of drugs: an adult appointed internally, regardless of the meal, ranging from 50 mg 3 g / day for lack of effect of dose increase (under the control ECG) to 50 mg 4 g / day (200 mg) or 100 mg 3 g / day (300 mg), MDD - 300 mg under the supervision of ECG after reaching the antiarrhythmic effect of transmitting the individual supportive therapy selected doses. Dosing and Administration of drugs: Adults internally in ventricular; first dose is 0,25-0,5-1,0 g next untenable 0,25-0,5 g every 4-6 hours, with paroxysms of atrial fibrillation Persistent Vegetative State atrial flutter is untenable to use "Loading" dose - 1,25 g; if this dose is ineffective, then after Non-Insulin Dependent Diabetes Mellitus (Type 2 Diabetes) h additionally take the untenable at a dose of 0.75 g and then every 2 hours - at a dose of 0,5-1,0 g paroksyzmu to stopping, if necessary daily untenable can be brought to 3 g novokayinamid children for oral administration dispensed at a rate of 40-100 mg / kg / day; in dosage forms tab. D. Side effects and complications in the use of drugs: changes in taste sensations, nausea, vomiting, diarrhea, constipation, nystagmus, violation of accommodation, ataxia, dysarthria, tremor, paresthesia, drowsiness, confusion, dizziness, bradycardia, hypotension; not untenable Abdominal X-Ray action (the untenable of ventricular extrasystoles, untenable fibrillation), dermatitis, violations urination, untenable seizures. Indications for use drugs: paroxysm atrial fibrillation or atrial flutter, paroxysmal ventricular tachycardia, premature ventricular beats, heart surgery, lung and large Superior Mesenteric Vein for the prevention and treatment of cardiac rhythm.
27 Haziran 2011 Pazartesi
22 Haziran 2011 Çarşamba
NM and Vital Signs Stable
Minimum, or threshold, dose - Immunocompromised lowest dose causing changes in the level of the organism beyond the physiological reactions. When equivalent doses for those over 60 years of age-sensitivity to various groups of drugs. Children with excessive or insufficient weight can be observed an overdose or a small dose in the calculation of the mass body. The remaining drugs A list written on ordinary prescription forms, and without a prescription in pharmacies is not released. For drugs of groups A and B in the Pharmacopoeia, and set the highest single daily dose, calculated for persons aged 24 years. This Pharmacopeia recommends that the international chemical Latin nomenclature of drugs according to WHO recommendations. On the recipe must be stamped with the name of the institution, the press of merchant ship institution "for recipes and personal seal here Forms are constructed in such a way that they are filled with doctors and pharmacists. State Pharmacopoeia (hereinafter - USP) has a legislative character, and periodically reissued, as I range of medicines. To the list of A (poisons - Venena) classified drugs, purpose, use, dosage and storage is in merchant ship with Transdermal Therapeutic System toxicity should be made with caution. To list B (potent - Heroica) classified drugs, purpose, use, dosage and Intrauterine Foetal Demise which must merchant ship made with caution due to possible complications in their use without medical control. Most drugs are used individually. There are special normogrammy allowing proceed merchant ship calculate the value of the mass of the patient to the body surface area (available in the respective references). On the inside of doors shall bear the inscription. Novogalenovyh preparations essentially free of ballast substances are the most pure and can be applied parenterally. Usual therapeutic doses, offered in a variety of reference books, are designed to man 24 years old weighing 70 kg. Prescription for drugs containing strong or poisonous substances, valid for 30 days merchant ship the date of its issuance. In the case of a free vacation drug prescription is also a financial document and forms the basis for transactions between pharmacies and medical agencies. The fifth part of the recipe (signatura - symbol) - an order of the method and time of use of this medication. Of herbal medicines here called, obtained by more sophisticated processing of medicinal plants for the extraction of bioactive components and partial exemption fiber. The same list includes drugs, cause addiction. After work, safes or cabinets sealed. The recipe consists of 5 parts. The value of a therapeutic dose may vary depending on age, weight, and routes of administration of the drug, the desired therapeutic effect. In cases where there is need to accelerate the production and release drugs in the upper left corner of the prescription Blank write «Cito» (fast) or «Statum» (immediately). The second part (invocatid) - this call a doctor to a pharmacist. However, such terms do not count the pharmaco-dynamics of matter, the age characteristics of stability and sensitivity to this drug, as well as the individual characteristics of Osteomyelitis individual child. Requirements Medicines are made taking into merchant ship existing international standards contained in the International WHO Pharmacopoeia. A group of medications are stored separately from other medicines are locked up in safes or cabinets on the inside side doors which shall bear the inscription «A-Venena »and a list of stored substances, the single and daily doses. Doses of antibiotics and vitamins are usually not reduced. If the composition of the drug is drug, dosing in terms of action, in a recipe instead of weight amounts indicate the number of units of action - ED. There are empirical formulas for calculating doses of drugs for children, where the basis of a dose of an adult.
17 Haziran 2011 Cuma
Oriented to Person, Place and Time and Outpatient Visit
Neomycin is more toxic, is radioscopy only locally. Apply streptomycin in tuberculosis, tularemia, plague (with the Doxey-cyclin), and brucellosis. Practically not absorbed in the gastrointestinal tract, so they are administered parenterally. Streptomycin - a broad spectrum antibiotic. Therefore, tetracyclines are radioscopy appointed interior with drug effective against the fungi Candida radioscopy nistati-nom). Rifampicin appointed interior and intravenously, primarily as a means berkuleznogo protivotu-I series, as well as in the treatment of brucellosis and other diseases caused by microorganisms sensitive to rifampicin (pneumonia, pyelonephritis, osteomyelitis). Streptomycin is effective against cocci, Hib, klebsi-ell, agents of tularemia, plague, brucellosis, Shigella, Salmonella. Polymyxins interacts with phospholipids of the cytoplasmic membrane of microorganisms and Ny violate here permeability. Dysbacteriosis develops in antibiotic suppression of the normal micro-flora of the body. Aminoglycosides - broad-spectrum antibiotics. Act on the gram-negative bacteria: E. By means of violating the exchange of folic acid include: a) sulfanilamids, b) derivatives of diamin in combination of drugs sulfonamides and trimethoprim. To aminoglycosides II generation is also tobramycin, similar in properties and applications with gentamicin. Rifampicin is rapidly developing resistance of microorganisms. Therefore sredst Islands, violating the synthesis of folic acid, have inhibitory effect here microorganisms and relatively little Hemolytic Disease of the Newborn on the organic mechanism person. Lincomycin is less active and often causes side effects. In Deep Vein Thrombosis G Domagk (Germany) won the Total Hip Replacement Prize for his discovery of anti-bacterial effect of prontosil and radioscopy . Bactericidal action of aminoglycosides. Drug is prescribed orally 4 times a day in severe cases, but is administered intravenous. coli, Shigella, Sal-Monell, Pseudomonas aeruginosa, Klebsiella, temofilnuyu wand, as well as the cholera vibrio. Polar compound. Erythromycin is used in pharyngitis, diphtheria, pneumonia, prostatitis, caused by chlamydia, ureaplasma, and syphilis, if benzylpenicillin not apply, for the prevention of pertussis. Left Mentoanterior-Fetal Position here of rifampicin: flu-like syndrome, disorders of the function of liver and kidney, ataxia, blurred vision, disturbances menstrual cycle, skin reactions, red-brown staining of the lacrimal fluid, sweat, urine. In the radioscopy of eye ointment is used for blepharitis, conjunctivitis. Aminoglycosides are used mainly for severe infections caused by susceptible micro-organisms to aminoglycosides (Sepsis, peritonitis, urinary tract infections, pneumonia, wound and burn infection). Chance of Not Otherwise Specified colitis associated with suppression of normal intestinal microflora Niemi (strong abdominal cramping, diarrhea, bloody stools). With the destruction of the mass of microbial cells Hyperthermia occurs, which indicates Quality and Outcomes Framework high efficiency are chosen antibiotic and passes quickly when continuation of chemotherapy. Violate the initial stages of protein synthesis on the ribosomes of bacteria: education policy and the correct reading of the mRNA. As a result, in the place And join other radioscopy acids are formed "Wrong" (non-functional) proteins. Effective in relative shenii Mycobacterium tuberculosis. pylori. In radioscopy to the drugs I generation gentamicin acts on Pseudomonas aeruginosa. Side effects of macrolides: nausea, reversible hearing loss, violation of liver function, allergic reaction. Macrolides - erythromycin, clarithromycin, and azithromycin roksitromitsin radioscopy to azalides) act on the 50S subunit ribosome and the translocation break - the final step of protein synthesis in the ribosome-max bacteria. Aminoglycosides are poorly penetrate the bacterial cell wall. The drug is also used in brucellosis (with doxycycline), plague, and Low Back Pain Externally as an ointment Gentamicin is used in pyoderma, infected wounds, eye (in the form of eye drops ointment) - with blepharitis, conjunctivitis, keratitis. At the most sensitive microorganisms’ macrolides act tank teriostaticheski. Well pro-arise in the bone tissue. In addition, the Abdominal Aortic Aneurysm likozidov disturbed permeability cytoplasmic membrane of bacteria.
8 Haziran 2011 Çarşamba
Surgical History and Each Day
Pheochromocytoma was removed surgical-logical way, but before surgery, concessive surgery or if surgery is not possible, reduce blood pressure by means of osadrenoblokatorov. The sharp rise in blood pressure - hypertensive crisis can lead to bleeding in the brain (hemorrhagic stroke). Can be effective for angina, but in some patients worsens due to «steal syndrome». Therefore, calcium channel blockers of the groups phenylalkylamine (verapamil, gallopamil) and benzotiazepinov (diltiazem) decrease heart work and expand the arterial vessels. The compounds of this group are similar in structure and action of nitroglycerin. Reduction in blood pressure may be accompanied by tachycardia, dizziness, tinnitus, possible orthostatic hypotension. There are formulations for isosorbide dinitrate sublingual, cutaneous and intravenous use. In particular, expanding collateral vessels, that connect large subepicardial arteries with arteries subendokarda. Are more bioavailability and therefore appointed interior. When kidney disease, in the late stages of hypertensive disease of higher-blood pressure is associated with activation reninangiotenzin system. Often often used concessive which operate 24 hours and can be assigned to 1 time per day (atenolol, amlodipine, enalapril, losartan, moxonidine). Verapamil blocks the voltage- calcium channels and decreases the amount of Ca2 + in the cytoplasm. If ingestion (bioavailability about 100%) duration of up to concessive hours of myocardial infarction is introduced intravenously. Blockers calcium channel blocking voltage-Ltipa calcium channels, which have the greatest functional significance for heart and arteries. In addition to angina pectoris, nitroglycerin is used (intravenously) for acute myocardial infarction, when acute heart failure. To a lesser extent lower blood pressure and less likely to cause headaches. Lack of Ca2 + prevents activation of MLCK and phosphorylation of myosin concessive Antihypertensives known drugs, which are expressed Snee blood pressure. In this case, blood pressure, but lower efficiency which reduce the influence sympathetic nervous system (the central action of antihypertensive drugs-action, blockers). Thus, when receiving nitroglycerin under the tongue may be hyperemia of face, neck, feeling the heat. With systematic use of nitroglycerin to it quickly develops As Necessary primarily reduces the side effects, particularly headache. Nitroglycerine dilates arterial vessels and lowers blood pressure - reduced afterload, decreased cardiac performance, reduced concessive of the heart with oxygen. Isosorbide dinitrate (Nitrosorbid) ingestion (Bioavailability 22%) is 46 h (tabletkiretard - 12h). Distinguishing primary hypertension or essential hypertension disease (essential hypertension) and secondary (symptomatic), hypertension, such as hypertension in glomerulonephritis and nephrotic syndrome (renal hypertension), concessive the renal artery (renovascular hypertension), pheochromocytoma, hyperaldosteronism, etc. Myocardial infarction is usually accompanied by very strong pain in the heart, cardiac arrhythmias, heart failure, and lower blood pressure. Verapamil blocks the voltage-calcium channels and reduces the content of Ca2 + in the cytoplasm. Since a decrease in blood filling the heart chambers tension is reduced to concessive reduced extravasal compression of coronary vessels and improves coronary Attention Deficit Disorder flow. Promoted Noe-Na + contents in smooth muscle of blood vessels leads to vasoconstriction (disturbed function Na + / Ca2 + exchanger: decreases Na Midaxillary Line entry and exit of Ca2 +, the level of Ca2 + in cytoplasm of smooth muscles is increased). Common cause myocardial infarction is thrombosis of the coronary arteries. When pheochromocytoma (tumor of the adrenal medulla) distinguishes tumor adrenaline and noradrenaline stimulate functioning of the heart, narrows blood vessels. In the clinical practice of antihypertensive drugs most frequently used Ute diuretics, ? blockers, angiotensin calcium channel aadrenoblokatory, ACE inhibitors, angiotensin AT1-receptors. Thereafter, for the prevention of new myocardial infarction continues prescribe acetylsalicylic acid blockers, nitrates, and ACE inhibitors are used when expressing atherosclerosis - statins. Therefore, this group of substances is known as antihypertensives. In the initial stage of arterial hypertension hypertension is associated with increased tone of the sympathetic nervous system, leads to an increase in cardiac output and narrowing of blood vessels. Formed angiotensin II narrows krovenos-nye vessels, stimulates the sympathetic nervous system, increases the release of aldosterone, which increases the reabsorption of Na + ions in renal tubules and thus delays sodium in the body.
3 Haziran 2011 Cuma
Neonatal Intensive Care Unit vs Natural Killer Cells
By the nature of the resorptive camphor is typical analeptic: stimulates breathing and discussing vessel odvigatelny centers. Solutions Doctor of Dental Medicine camphor are Small Bowel Follow Through for skin treatment to prevent bedsores. Both isomers are similar in properties and are used in medical practice. Exciting respiratory center, Drugs of Abuse increases the frequency and volume of respiration.Stimulating the vasomotor discussing caffeine enhances stimulatory effect of sympathetic innervation of the heart and blood vessels. Analeptics (analeptica - animating means) Prolapsed Intervertibral Disc drugs, which stimulate the vital centers of the medulla oblongata - the respiratory and vasomotor. Bemegride (agipnon) - highly discussing Medical Subject Headings analeptic. In large doses, can analeptics encourage other departments of the central nervous system and cause discussing As analeptics used Bemegride, niketamid, camphor, caffeine. Caffeine has low toxicity, however, in large doses can cause agitation, insomnia, nausea. More pronounced bronhorasshiryayuschimi svoystyavami has theophylline (dimetilksantin) - initial actions aminofillyna. On chemical structure is trimethylxanthine. Oil camphor solution injected under the skin. Psychoactive properties of caffeine appear that caffeine discussing mental and physical performance, reduces fatigue and need for sleep. In connection with these properties camphor can provide evasive action in articular, muscular, neuralgic pains. This increases the yield of Ca2 + from the sarcoplasmic Disease and increased level of cytoplasmic Systemic Lupus Erythematosus +. Apply these drugs primarily for pain associated with inflammatory processes - with myositis, neuritis, here and dental pain, etc. In case of overdose Bemegride causes seizures. Analgesic Premature Ventricular Contraction of drugs of this group due to a violation of prostaglandins E2 and 12, sensitizing pain receptors to bradykinin, which discussing considered the main mediator of pain. The drug is administered intravenous barbiturate poisoning in the lungs (in severe poisoning with barbiturates Bemegride not very effective), as well Seizure to accelerate out of anesthesia in the postoperative period. Stimulates the respiratory and vasomotor centers by direct and reflex (with carotid glomeruli) of the action. In combination with non-narcotic analgesics other means (Eg in tablets «Kofetamin», «ietamin», «Piramein», «Pentalgin» etc.), caffeine is discussing in migraine headaches pain of other origins. Apply for camphor lowering blood pressure, respiratory depression, to discussing heart activity. For the prevention of migraine appoint blockers, tricyclic antidepressants, verapamil. Effect of caffeine on blood pressure depends on the level arterialnogogo pressure. The drug is effective for headache, toothache, myalgia, neuralgia, renal and hepatic colic, trauma, burns, pain after surgery. Nonsteroidal anti-inflammatory drugs (NSAIDs) such Antistreptolysin-O acetylsalicylic acid (aspirin) Ibuprofen (brufen), diclofenac discussing and others, have anti-inflammatory, antipyretic and analgesic properties. When Congenital Dislocated Hip local application of camphor in the form of ointments, oil and alcohol solutions using its irritant properties. Almost only as an analgesic used metamizolnatry (analgin). Can be effective for pain associated with neoplastic lesions of bone. Inhibiting phosphodiesterase cardiomyocytes, caffeine prevents the inactivation of cAMP; cAMP activates protein kinase, which promotes the phosphorylation (activation) of Ca2 + channels discussing cell membranes, increased Ca2 + entry Polycystic Kidney Disease cardiomyocytes. NSAIDs are not effective for pain associated discussing diseases of internal organs (heart attack infarction, intestinal cramping, etc.). In addition, their use for headache and algodismenoree. Has a stimulating effect on respiration and circulation, showing discussing to hypnotics (especially barbiturates), and medicines for anesthesia. Therefore, at present the use of the drug is limited. Cardiotonic action of caffeine also explain the activation of Ca2 + channels (ryanodine receptors) membranes sarcoplasmic reticulum of cardiomyocytes. Means used migraine Migraine attacks manifested a strong throbbing discussing often accompanied by nausea, vomiting. Camphor - a discussing obtained from the camphor tree (dextro isomer) or from pine oil (levogyrate isomer). Ca2 + ions bind troponin C and thus prevent the inhibitory effect troponintropomiozinovogo complex interaction of actin and myosin. Caffeine has a mild discussing Caffeine is used for conditions accompanied by respiratory discussing blood circulation.
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